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Howard A Burris Selected Research

Carboplatin (JM8)

12/2019A Randomized, Double-Blinded, Phase II Trial of Carboplatin and Pemetrexed with or without Apatorsen (OGX-427) in Patients with Previously Untreated Stage IV Non-Squamous-Non-Small-Cell Lung Cancer: The SPRUCE Trial.
1/2018Amrubicin and carboplatin with pegfilgrastim in patients with extensive stage small cell lung cancer: A phase II trial of the Sarah Cannon Oncology Research Consortium.
1/2018Randomized phase 2 trial of pemetrexed, pemetrexed/bevacizumab, and pemetrexed/carboplatin/bevacizumab in patients with stage IIIB/IV non-small cell lung cancer and an Eastern Cooperative Oncology Group performance status of 2.
1/2018Phase II trial of preoperative pemetrexed plus carboplatin in patients with stage IB-III nonsquamous non-small cell lung cancer (NSCLC).
9/2017First-Line Carboplatin, Pemetrexed, and Panitumumab in Patients with Advanced Non-Squamous KRAS Wild Type (WT) Non-Small-Cell Lung Cancer (NSCLC).
12/2015A first-in-human phase I dose-escalation, pharmacokinetic, and pharmacodynamic evaluation of intravenous LY2090314, a glycogen synthase kinase 3 inhibitor, administered in combination with pemetrexed and carboplatin.
10/2012Phase II trial of ixabepilone and carboplatin with or without bevacizumab in patients with previously untreated advanced non-small-cell lung cancer.
9/2012A phase I trial of oral administration of panobinostat in combination with paclitaxel and carboplatin in patients with solid tumors.
8/2012Phase I study of pazopanib in combination with paclitaxel and carboplatin given every 21 days in patients with advanced solid tumors.
8/2012Phase II study of maintenance sunitinib following irinotecan and carboplatin as first-line treatment for patients with extensive-stage small-cell lung cancer.
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Howard A Burris Research Topics

Disease

117Neoplasms (Cancer)
01/2024 - 01/2002
66Breast Neoplasms (Breast Cancer)
01/2024 - 01/2002
25Neutropenia
01/2023 - 05/2003
21Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 05/2005
17Disease Progression
05/2024 - 04/2003
16Thrombocytopenia (Thrombopenia)
10/2019 - 02/2002
16Diarrhea
01/2019 - 05/2003
14Carcinoma (Carcinomatosis)
12/2021 - 03/2002
13Fatigue
01/2019 - 12/2007
13Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2018 - 05/2002
10Nausea
01/2018 - 11/2005
9Vomiting
01/2019 - 11/2005
9Neoplasm Metastasis (Metastasis)
03/2016 - 04/2008
8Exanthema (Rash)
01/2019 - 12/2007
8Febrile Neutropenia
01/2018 - 02/2002
8Colorectal Neoplasms (Colorectal Cancer)
05/2015 - 08/2007
7Anemia
01/2018 - 06/2010
6Ovarian Neoplasms (Ovarian Cancer)
01/2023 - 05/2010
5Mucositis
10/2017 - 05/2009
5Melanoma (Melanoma, Malignant)
03/2016 - 09/2010
4Renal Cell Carcinoma (Grawitz Tumor)
11/2020 - 12/2007
4Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2018 - 10/2002
4Infections
01/2018 - 10/2011
4Prostatic Neoplasms (Prostate Cancer)
08/2017 - 03/2007
4Stomatitis
02/2017 - 02/2012
4Fever (Fevers)
01/2017 - 10/2008
4Pancreatic Neoplasms (Pancreatic Cancer)
04/2013 - 03/2005
3Hyperglycemia
01/2024 - 02/2012
3Lymphoma (Lymphomas)
01/2023 - 03/2007
3Pain (Aches)
08/2018 - 09/2015

Drug/Important Bio-Agent (IBA)

26Carboplatin (JM8)FDA LinkGeneric
12/2019 - 03/2002
22Paclitaxel (Taxol)FDA LinkGeneric
08/2017 - 01/2002
21Hormones (Hormone)IBA
12/2023 - 03/2010
21Trastuzumab (Herceptin)FDA Link
10/2023 - 01/2004
18EverolimusFDA Link
12/2023 - 04/2008
18Bevacizumab (Avastin)FDA Link
11/2023 - 12/2007
17GemcitabineFDA Link
05/2024 - 03/2002
14Ado-Trastuzumab EmtansineIBA
11/2019 - 06/2010
14Docetaxel (Taxotere)FDA Link
01/2017 - 05/2005
12ErbB Receptors (EGF Receptor)IBA
10/2023 - 08/2005
11exemestane (Aromasin)FDA Link
12/2023 - 02/2012
11Irinotecan (Camptosar)FDA LinkGeneric
01/2015 - 05/2003
10taxaneIBA
11/2019 - 01/2002
9PlatinumIBA
01/2023 - 02/2002
9Aromatase InhibitorsIBA
01/2021 - 02/2012
9Immunoconjugates (Immunoconjugate)IBA
01/2020 - 06/2010
9Pemetrexed (MTA)FDA Link
12/2019 - 01/2010
8Biomarkers (Surrogate Marker)IBA
11/2023 - 08/2013
8human ERBB2 proteinIBA
10/2023 - 02/2011
8Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2018 - 12/2007
7Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2023 - 06/2008
7Angiogenesis InhibitorsIBA
11/2023 - 01/2010
7pertuzumabIBA
10/2023 - 09/2012
7Doxorubicin (Adriamycin)FDA LinkGeneric
08/2017 - 06/2008
7ixabepilone (BMS 247550)FDA Link
08/2017 - 03/2007
7Monoclonal AntibodiesIBA
04/2013 - 03/2010
6Epidermal Growth Factor (EGF)IBA
12/2023 - 05/2010
6pegfilgrastim (Neulasta)FDA Link
01/2018 - 06/2008
6Capecitabine (Xeloda)FDA Link
02/2014 - 01/2010
6Lapatinib (GW572016)FDA Link
06/2011 - 01/2004
6Topotecan (Hycamtin)FDA LinkGeneric
05/2011 - 05/2002
5Fulvestrant (Faslodex)FDA Link
01/2024 - 06/2011
5Letrozole (Femara)FDA LinkGeneric
10/2022 - 11/2016
5ribociclibIBA
10/2022 - 11/2016
5Estrogen ReceptorsIBA
01/2020 - 05/2013
5pazopanibFDA Link
01/2018 - 01/2010
5TOR Serine-Threonine KinasesIBA
01/2016 - 04/2008
5Epothilones (Epothilone)IBA
10/2012 - 03/2007
4Immune Checkpoint InhibitorsIBA
05/2024 - 05/2016
4Proteins (Proteins, Gene)FDA Link
01/2024 - 04/2006
4Phosphotransferases (Kinase)IBA
01/2024 - 01/2004
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2023 - 06/2011
4rucaparibIBA
01/2023 - 08/2017
4atezolizumabIBA
01/2022 - 11/2014
4Sorafenib (BAY 43-9006)FDA Link
11/2017 - 05/2010
4Aspartate Aminotransferases (Aspartate Transaminase)IBA
08/2017 - 05/2011
4dabrafenibIBA
03/2016 - 11/2012
4trametinibIBA
03/2016 - 08/2012
4AnthracyclinesIBA
12/2014 - 04/2009
4Fluorouracil (Carac)FDA LinkGeneric
07/2012 - 01/2002
4Cetuximab (Erbitux)FDA Link
07/2010 - 08/2007
4Vinorelbine (Navelbine)FDA LinkGeneric
08/2009 - 04/2003
3AlpelisibIBA
01/2024 - 01/2018
3Tyrosine (L-Tyrosine)FDA Link
01/2023 - 01/2004
3AndrogensIBA
01/2022 - 03/2007
3Poly(ADP-ribose) Polymerase InhibitorsIBA
12/2021 - 08/2017
3Anastrozole (Arimidex)FDA LinkGeneric
01/2021 - 06/2011
3Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2021 - 11/2016
3Mechanistic Target of Rapamycin Complex 1IBA
11/2020 - 04/2013
3Messenger RNA (mRNA)IBA
12/2019 - 04/2013
3Tumor Biomarkers (Tumor Markers)IBA
11/2019 - 01/2019
3Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2019 - 10/2017

Therapy/Procedure

62Therapeutics
12/2023 - 07/2002
29Drug Therapy (Chemotherapy)
11/2023 - 07/2002
7Radiotherapy
01/2016 - 07/2002
6Neoadjuvant Therapy
11/2015 - 06/2008
4Immunotherapy
11/2023 - 09/2010
4Combination Drug Therapy (Combination Chemotherapy)
01/2018 - 03/2002
4Aftercare (After-Treatment)
01/2016 - 05/2010
3Intravenous Infusions
01/2020 - 11/2010